1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-173356
    Antiparasitic agent-26
    Inhibitor
    Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that potently inhibits the growth of Naegleria fowleri, with IC50 values of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). Antiparasitic agent-26 exerts its antiparasitic activity by inducing programmed cell death, including cytoplasmic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be used in the research of primary amoebic meningoencephalitis (PAM).
    Antiparasitic agent-26
  • HY-N14197
    Hynapene B
    Inhibitor
    Hynapene A inhibits Eimeria tenella with a MIC of 34.7 μM.
    Hynapene B
  • HY-117375
    Brotianide
    Inhibitor
    Brotianide is a potent anti-parasitic agent. Brotianide can be used to study liver fluke and gastric fluke infestations.
    Brotianide
  • HY-A0148AR
    Halofantrine hydrochloride (Standard)
    Inhibitor
    Halofantrine (hydrochloride) (Standard) is the analytical standard of Halofantrine (hydrochloride). This product is intended for research and analytical applications. Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound.
    Halofantrine hydrochloride (Standard)
  • HY-12538R
    Graveoline (Standard)
    Inhibitor
    Graveoline (Standard) is the analytical standard of Graveoline (HY-12538). This product is intended for research and analytical applications. Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury.
    Graveoline (Standard)
  • HY-119419S
    Pirimicarb-d6
    Pirimicarb-d6 is the deuterium labeled Pirimicarb (HY-119419). Pirimicarb is a fast-acting selective carbamate insecticide on a wide range of crops including cereals, sugar beet, potatoes, fruits and vegetables. Pirimicarb is an AChE inhibitor and an acaricide.
    Pirimicarb-d<sub>6</sub>
  • HY-13834
    GW844520
    Inhibitor
    GW844520 is an orally active inhibitor of cytochrome bc1 complex. GW844520 can be used in malaria and anti-plasmodium related research.
    GW844520
  • HY-N2927
    Costic acid
    Inhibitor
    Costic acid (β-Costic acid) is a natural product, that can be isolated from Dittrichia viscosa. Costic acid exhibits potent in vivo acaricidal activity against the parasite. Costic acid is not toxic for human umbilical vein endothelial cells (HUVEC) at concentrations of up to 230 μM. Costic acid can be used for the research of varroosis in honey bee colonies.
    Costic acid
  • HY-N7141R
    Spiramycin I (Standard)
    Inhibitor
    Spiramycin I (Standard) is the analytical standard of Spiramycin I. This product is intended for research and analytical applications. Spiramycin I is a macrolide antibiotic and antiparasitic.
    Spiramycin I (Standard)
  • HY-N14309
    Astechrome
    Inhibitor
    Astechrome is a natural product with a strong antimalarial activity with an IC50 value of 0.94 μM. Astechrome exhibits cytotoxicity against Vero cells with IC50 value of 7.9 μM.
    Astechrome
  • HY-12638R
    Dichlorophen (Standard)
    Inhibitor
    Dichlorophen (Standard) is the analytical standard of Dichlorophen (HY-12638). This product is intended for research and analytical applications. Dichlorophen is a chlorophenol antimicrobial agent that can destroy the integrity of microbial cell membranes and interfere with the activity of metabolic enzymes. Dichlorophen can covalently bind to the thiol groups of microbial proteins and has broad-spectrum antibacterial, antifungal and anthelmintic activity. Dichlorophen can be used as an antimicrobial agent in the study of drug-resistant bacterial infections.
    Dichlorophen (Standard)
  • HY-134013
    Piperitenone oxide
    Inhibitor
    Piperitenone oxide (lippione), a monoterpene, can be isolated from the n-hexane extract from spearmint (Mentha spicata) leaves. Piperitenone oxide is a potent inducer of differentiation in a RCM-1 human colon cancer cell line.
    Piperitenone oxide
  • HY-118769
    Japonilure
    Japonilure serves as an agent for insecticides and pheromones.
    Japonilure
  • HY-B1851R
    Hexythiazox (Standard)
    Inhibitor
    Hexythiazox (Standard) is the analytical standard of Hexythiazox. This product is intended for research and analytical applications. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites.
    Hexythiazox (Standard)
  • HY-169816
    MMV03
    Inhibitor
    MMV03 is an anti-malaria agent, and is active against P. falciparum (EC50: 0.6 μM).
    MMV03
  • HY-118996B
    Isometamidium chloride hydrochloride
    Inhibitor
    Isometamidium chloride hydrochloride is an antiprotozoal agent, that exhibits activity against trypanosome. Isometamidium chloride hydrochloride can be used in research of african sleeping sickness.
    Isometamidium chloride hydrochloride
  • HY-175493
    CRT-IN-1
    Inhibitor
    CRT-IN-1 (compound 6x) is a potent chloroquine resistance transporter (CRT) inhibitor with an IC50 of 0.33 μM. CRT-IN-1 has activity.
    CRT-IN-1
  • HY-W745644
    (Z)-7-Hexadecenal
    (Z)-7-Hexadecenal is a sex pheromone that attracts male insects, isolated from female Heliothis virescens moths.
    (Z)-7-Hexadecenal
  • HY-169169
    Insecticidal agent 14
    Inhibitor
    Insecticidal agent 14 (compound 8a) shows potent insecticidal activity against Plutella xylostella and Mythimna separata, with LC50 values of 0.79 and 9.17 mg/L against P. xylostella, respectively, and 3.58 and 83.09 mg/L against M. separata, respectively.
    Insecticidal agent 14
  • HY-B2186R
    Piperazine adipate (Standard)
    Inhibitor
    Piperazine adipate (Standard) is the analytical standard of Piperazine adipate. This product is intended for research and analytical applications. Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate (Standard)

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